HexaTest Hardcore Pro Series

What does HexaTest Hardcore Pro Series do?
The key ingredient in HexaTest increases Testosterone Recepter Concentration.

The Science Behind Hexatest Hardcore Pro Series

A key study, published in the prestigious journal of Medicine & Science in Sports & Exercise, used a randomized, double-blind, placebo-controlled cross-over design protocol to test how 10 previously trained male subjects reacted to the same key compound found in the HexaTest formula. The study results showed this key compound can in fact amplify your body's testosterone (androgen) receptor concentration in just 21 days! Researchers in this study theorized that this lead to greater cellular uptake of testosterone.

Background
D-Aspartic acid is an amino acid present in Neuroendocrine tissues, invertebrates and vertebrates, including rats and humans. Here we investigated the effect of this amino acid on the release of LH and testosterone in the serum of humans and rats. Furthermore, we investigated the role of D-aspartate in the synthesis of LH and testosterone in the pituitary and testes of rats, and the molecular mechanisms by which this amino acid triggers its action.

Methods
For humans: A group of 23 men were given a daily dose of D-aspartate (DADAVIT ®) for 12 days, whereas another group of 20 men were given a placebo. For rats: A group of 10 rats drink a solution of either 20 mM D-aspartate or a placebo for 12 days. Then LH and testosterone accumulation was determined in the serum and D-aspartate accumulation in tissues. The effects of D-aspartate on the synthesis of LH and testosterone were gauged on isolated rat pituitary and Leydig cells. Tissues were incubated with D-aspartate, and then the concentration (synthesis) of cGMP in the pituitary and LH and of testosterone and cAMP in the Leydig cells was determined.

Results
In humans and rats, sodium D-aspartate induces an enhancement of LH and testosterone release. In the rat pituitary, sodium D-aspartate increases the release and synthesis of LH through the involvement of cGMP as a second messenger, whereas in rat testis Leydig cells, it increases the synthesis and release of testosterone and cAMP is implicated as second messenger. In the pituitary and in testes D-Asp is synthesized by a D-aspartate racemase which convert L-Asp into D-Asp. The pituitary and testes possesses a high capacity to trapping circulating D-Asp from hexogen or endogen sources.

Conclusion
D-aspartic acid is a physiological amino acid occurring principally in the pituitary gland and testes and has a role in the regulation of the release and synthesis of LH and testosterone in humans and rats.